Question 1

Is Tirzepatide right for me?

Accepted Answer

Tirzepatide is typically suitable for adults seeking substantial weight loss, especially if your BMI is over 27 with weight-related conditions or over 30. It's not recommended for people with a history of medullary thyroid cancer, pancreatitis or severe gastrointestinal disease.

Question 2

What results were seen in Tirzepatide's clinical trials?

Accepted Answer

Clinical trials show weight-loss of up to 20.9% over 72 weeks. Most users notice reduced appetite and cravings within the first few weeks, with steady weight loss thereafter. It's important to note that compounded medications should not be presumed equivalent to their branded counterparts, and they are not reviewed by the FDA for safety or effectiveness.

Question 3

How is Tirzepatide different from Semaglutide?

Accepted Answer

Tirzepatide is a dual agonist that targets both GLP-1 and GIP receptors, while semaglutide only targets GLP-1. This dual action often yields greater weight-loss results.

Question 4

What are the side effects of Tirzepatide?

Accepted Answer

The most common side effects are GI-related – nausea, constipation, diarrhea, vomiting, and stomach discomfort – and they often improve over time. We start low and increase doses gradually to help minimize side effects. Rare but serious risks have been reported, including pancreatitis, gallbladder problems, and kidney injury. Tell your care team before surgery/anesthesia, since GLP-1s can slow gastric emptying.

Animal studies indicated a risk of thyroid C-cell tumors. The correlation to humans has not been established, but you should avoid GLP-1 medications if you or your family has a history of MTC or MEN2. Review Important Safety Information for full details.

Question 5

Are the injections painful?

Accepted Answer

Most patients find them virtually painless. Our medications are administered subcutaneously (under the skin) — not intramuscularly — using the small insulin syringes our pharmacies send you. At 29–32 gauge, these needles are way finer and shorter than the 22–24 gauge needles you're accustomed to for things like flu shots. (Higher gauge = thinner needle.)

Question 6

Why is your formulation compounded with glycine?

Accepted Answer

Glycine is included for two reasons: it buffers the formulation for better stability and injection comfort, and it has preclinical evidence for preserving lean muscle mass during a caloric deficit.

That second reason matters when you're losing weight fast on a GLP-1. Standard GLP-1 weight loss can result in 25–40% of lost weight coming from lean tissue — a problem for first responders who depend on functional strength on the job. Pairing the active peptide with glycine is one way we tailor the formulation to the population we serve.

Glycine isn't a substitute for training or protein intake, and individual results vary.

Eat protein, lift heavy, take your shot.

Question 7

Does RespondWell require insurance?

Accepted Answer

No. We don't require insurance. You'll see clear pricing and can pay with HSA/FSA or credit/debit.

Question 8

How does RespondWell work?

Accepted Answer

Start with a quick health intake, connect with a licensed provider, and get personalized care – delivered to your door. RespondWell's care doesn't end when your medication arrives. Reach your care team 24/7 through secure messaging.

Question 9

How does my consultation work?

Accepted Answer

In most states your consultation is asynchronous — you complete a secure intake and a licensed clinician reviews it, typically in under 4 hours, with no live appointment required.

Here's how it works:

1. Complete your intake: Fill out a secure health questionnaire and add any questions or concerns.
2. Clinician review: A licensed provider reviews your intake, typically in under 4 hours.
3. Next steps: If everything is clear, and treatment is medically appropriate, your provider may issue a prescription. If more information is needed, your provider will message you with follow-up questions so you can respond on your schedule.

Some states require a live visit. If that applies to you, you'll choose a time and meet by phone or video:
Louisiana, Mississippi, Arkansas, Georgia, New Mexico, Tennessee, Virginia, West Virginia.

Testosterone Replacement Therapy (TRT): video consultations are required in all states.

You're not on your own after a prescription is issued. Message your provider via your patient portal anytime, or contact support via portal or text message.

Question 10

How does RespondWell handle billing and shipping?

Accepted Answer

Our plans are fully inclusive – your consultation, medication, injection supplies, and 2-day shipping are all covered, with no hidden membership fees.

When you start a consultation or order, a temporary authorization hold is placed on your card. If treatment isn't approved by your clinician, the hold is released or refunded promptly, though the exact timing depends on your bank. If labs were required prior to a denial, your refund will be issued minus the laboratory fees.

Once approved, your medication is shipped directly to you in discreet, temperature-controlled packaging (where required) via free expedited shipping. To ensure you never miss a dose, refills are processed automatically on 1-month and 3-month plans, but you're always in control – you can pause or cancel your subscription anytime through your portal. Pause/cancellation requests must be made prior to medication shipment.

Good to know: Because we work with a nationwide pharmacy network to ensure fast delivery, your actual packaging might look different than the images on our site.

Question 11

Does RespondWell use licensed pharmacies?

Accepted Answer

Yes, all medications are sourced through U.S.-based compounding pharmacies that follow strict regulatory and safety guidelines. You receive high-quality, pharmacy-grade treatments – always.

Question 12

Is RespondWell a pharmacy or manufacturer?

Accepted Answer

No. Your medication is dispensed and (if applicable) compounded by licensed pharmacies.

Question 13

Who are your pharmacy partners?

Accepted Answer

RespondWell works with a network of licensed pharmacy partners to fulfill prescriptions when approved by a licensed clinician. Pharmacy selection may vary by treatment, location, pharmacy licensing, and medication availability.

View our most updated pharmacy partner list here: Our Pharmacy Partners

Question 14

Who are your medical providers?

Accepted Answer

Independent clinical services are provided by:

Arora Health & Aesthetics
CMO Shannon Arora, MD
300 Lenora Street
Seattle, WA 98121
https://www.arora-health.com

Licensed in all 50 States + DC.

Question 15

Why do you need my credit card before my prescription is approved?

Accepted Answer

We collect your credit card as part of our secure checkout and identity verification process. Verifying that your card is active helps ensure that, if a licensed clinician approves your prescription, your order can be processed promptly and sent to the pharmacy without unnecessary delays.

At this stage, your card is not charged for the treatment. We only place a temporary authorization hold to confirm the card is active.

Question 16

What happens if my prescription is not approved?

Accepted Answer

If your prescription is not approved by the licensed clinician, your order will not move forward and the temporary authorization hold will be voided.

Our intake process screens for major disqualifying factors before you reach the thank-you page, so reaching that step generally means there is a reasonably high likelihood that you may be medically eligible for the treatment requested. Final eligibility, however, is always determined by the reviewing clinician.

If your prescription is approved, your card will be charged and your order will be sent to the pharmacy for fulfillment.

Question 17

Is RespondWell LegitScript Certified?

Accepted Answer

Yes. RespondWell is LegitScript certified — and so are our partner Medical Group and pharmacy partners. LegitScript is the gold standard for telehealth verification, and we cleared their review because we operate the right way: licensed providers, FDA-registered pharmacies, and zero shortcuts. If you've dealt with sketchy online "clinics" before, this is how you know we're not that.

Tirzepatide

How it works

Start from your phone

A clinician reviews your requested treatment

Your treatment ships

What Tirzepatide can do

Frequently asked questions

Safety information

Boxed warning: thyroid C-cell tumors

About Our Medications

Medical Consultation Required

Clinical References

Related treatments

Semaglutide

More on Tirzepatide