Weight loss

    Weight loss care built around the shift.

    Clinician-guided GLP-1 treatment, delivered to your door. No membership fee.

    Plans from $109/month

    RX required · You pay $0 if you aren't approved · Important Safety Information

    Off-duty firefighter packing a meal in a station kitchen after an overnight shiftRespondWell treatment kit: medication vial, syringes and alcohol pads
    4.8 patient ratingLicensed cliniciansSupplies and shipping included

    Choose your treatment

    Same price for every dose. No membership or consultation fees.

    Tirzepatide vial and treatment kit

    Tirzepatide

    Dual-action GLP-1/GIP treatment

    From $116/month

    Weekly injection

    Explore Tirzepatide
    Semaglutide vial and treatment kit

    Semaglutide

    Established GLP-1 treatment

    From $109/month

    Weekly injection

    Explore Semaglutide
    Off-duty responder leaving a gym at dawn with a work bag

    This was never a discipline or willpower problem.

    Our clinicians understand the havoc wreaked by overnight shifts, interrupted sleep and meals that do not happen at normal hours.

    Read: shift work and metabolic health

    How it works

    Smiling man in gym clothing starting a health intake on his phone

    Start

    Start from your phone

    Answer a few questions about your health and goals.

    Video visit with a licensed clinician on a phone screen

    Review

    A clinician reviews it

    They decide whether treatment is appropriate. No video visit required in 41 states.

    RespondWell compounded tirzepatide weight loss vial with syringes and alcohol prep pads

    Delivered

    Your treatment ships

    Your medication arrives at your doorstep, by this time next week (if not sooner!)

    Patient at his kitchen counter early in the morning
    The process was clear, the medication arrived when they said it would, and I could message someone when I had a question.
    H.G. · Verified patient

    4.8 average from 290 patient reviews. Read all reviews

    *Individual results may vary.

    Common questions

    The most common side effects are GI-related – nausea, constipation, diarrhea, vomiting, and stomach discomfort – and they often improve over time. We start low and increase doses gradually to help minimize side effects. Rare but serious risks have been reported, including pancreatitis, gallbladder problems, and kidney injury. GLP-1s also carry a thyroid C-cell tumor warning based on animal studies (avoid if you or your family has MTC or MEN2). Tell your care team before surgery/anesthesia, since GLP-1s can slow gastric emptying. Review Important Safety Information for full details.

    Both medications are administered once weekly via a simple subcutaneous injection. We provide complete training and supplies so you feel confident with the process. Most patients find it much easier than expected.

    Tirzepatide is typically suitable for adults seeking substantial weight loss, especially if your BMI is over 27 with weight-related conditions or over 30. It's not recommended for people with a history of medullary thyroid cancer, pancreatitis or severe gastrointestinal disease.

    Clinical trials show weight-loss of up to 20.9% over 72 weeks. Most users notice reduced appetite and cravings within the first few weeks, with steady weight loss thereafter. It's important to note that compounded medications should not be presumed equivalent to their branded counterparts, and they are not reviewed by the FDA for safety or effectiveness.

    Semaglutide is suited for adults seeking proven weight-loss results at a lower price point. It's generally recommended for people with a BMI over 27 (with weight-related conditions) or over 30, but not for those with certain thyroid cancers or severe gastrointestinal issues.

    Boxed warning

    Tirzepatide and semaglutide caused thyroid C-cell tumors in rodents. It's unknown whether they cause medullary thyroid carcinoma in humans. Don't use if you or a family member has had medullary thyroid carcinoma or MEN 2.

    Full safety information and references

    Find out what you qualify for.

    Plans from $109/month. You pay $0 if you aren't approved.